Desmoplastic Fibroblastoma of the Finger Tip in an Adult

differential diagnosis is needed. Kraus et al. [3] examined 27 cases of xanthogranuloma. The mononuclear and xanthoma cells and most of the Touton cells exhibited reactivity for fascin and CD68, although 26 of 27 were reactive for HLA-DR, 25 of 27 for factor XIIIa, 25 of 27 for CD45, and 21 of 27 for CD4. None of the cases showed reactivity for CD1a, CD3, CD21, CD34, or CD35 [3]. When the patient visited our clinic, we performed shave biopsy because we needed a more accurate diagnosis. Without an accurate diagnosis of xantho-granuloma, there is a greater chance of surgical exci-sion. If surgical excision was performed, the patient would be left with a surgical scar and distortion of the nasal tip. Punch biopsy is very commonly used in the initial assessment of suspicious cutaneous lesions. Punch biopsy, however, is limited in diameter. It may not encompass the entire periphery of the lesion, preventing the pathologist from being able to assess key pathologic features such as symmetry, overall size, and circumscription. This partial sampling can lead to misdiagnosis. The most significant aesthetic problem of such a cutaneous mass is protrusion. Shave biopsy provides the advantage of partial removal without any extension of the lesion [5]. Therefore, we prefer shave biopsy over punch biopsy. In conclusion, the clinical diagnosis of typical xan-thogranuloma is easily made. However, as our case shows, xanthogranuloma can occasionally develop in an unexpected age group such as adolescents. For an accurate diagnosis, a histopathological examination is mandatory. This case illustrates a rare case of xantho-granuloma in adolescence, which was diagnosed based on histological findings, while invasive surgery, with its accompanying aesthetic compromise, was avoided. decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations. Am xanthogranuloma: an immunophenotypic study with a reappraisal of histogenesis. A case of multiple xanthogranuloma in adolescent. Korean J Dermatol Desmoplastic fibroblastoma is a rare neoplasm characterized by spindle-to satellite-shaped fibroblastic cells that are sparsely distributed in a collagenous stroma. It was first described in 1995 by Evans [1], who reported seven cases of morphologically distinct , benign, fibrous, soft tissue tumors and gave this specific tumor type its name. Since the characterization of this tumor by Evans, fewer than 100 cases have been reported in the Eng-lish literature. Only 7.9% of 63 cases of desmoplastic fibroblastoma in one analysis were hand lesions. Furthermore , there is only one report of …